Any Person required to obtain a Certificate of Registration under this Article shall notify the Director within 10 days of any relevant or material change in the information contained in the application or of other relevant circumstances, including but not limited to, if the Person acquires an additional Biological Agent Detector, ceases to possess a Biological Agent Detector, or modifies the training, notification, or response plans for the Biological Agent Detector. Upon notification of such change, the Director may suspend, revoke, or amend the registration or direct that the Certificate of Registration holder submit an application for a new registration. If Director instructs a Person to submit an application for a new registration, that Person must do so within 30 days of the mailing of the notice by the Director.