All operations or activity on a site within which explosive materials are used, stored, or handled shall be subject to such further additional or more restrictive requirements or conditions as the Department may determine; these may include requirements or conditions as to arrangements within buildings, including requirements for protective structures or devices, rules and regulations respecting smoking, fires, combustion of any kind, amounts and arrangements of material number and qualifications of employees or other persons on the premises, or any other condition, requirement, rule, or regulation determined by the Department to be necessary or appropriate for the protection of persons or property. Any such determination may be modified, amended, or enlarged, or superseded as the Department may at any time determine. The effective date and time of each determination shall be stated therein and any determination which effects a change in one previously fixed may be effective in 24 hours after service thereof, or later, as allowed by the Department. Failure to comply with or obey any determination shall result in the revocation of any permit held by the person to whom such determination is addressed.